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Stomach

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  • The stomach is a muscular organ located in the left side of the upper abdomen

  • It is a food reservoir and it can hold upto 1 litre of food 

  • The main function of stomach is food digestion (Breaking a large insoluble food molecules into smaller soluble food molecules) 

  • Digestion in the stomach involves both mechanical and chemical digestion

    • Mechanical digestion

      • Contractions of smooth muscle of stomach lead to mixing and grinding of food resulting in smaller food particles 

    • Chemical digestion

      • Stomach glands secret  enzymes (pepsin) & hydrochloric acid and with the help of acid and enzymes, food particles are further digested to form a thick liquid food known as chyme

  • Finally, the chyme is periodically emptied into the duodenum through pyloric sphincter for further digestion and absorption in the small intestine

  • Solid food emptying time is 3-4 hours and liquid food emptying time is around 30 minutes

  • Although the main function of stomach is food digestion and not absorption, there are few substances which are absorbed in stomach 

    • Water in case of dehydration

    • Drugs such as aspirin

    • 10–20% of ingested alcohol etc.

Common disorders of stomach

  • Dyspepsia

    • It is a commonest problem characterised by variety of symptoms including nausea, bloating after meals, pain, discomfort etc.

  • Gastroesophageal reflux disease (GERD)

    • Stomach contents, including acid, may reflux upwards into the esophagus occasionally which is a normal phenomenon in healthy people 

    • However, when the reflux becomes more frequent & bothers the patient it is called as GERD

  • Gastritis

    • It is the inflammation of the stomach characterised by nausea and/or pain

    • It can be caused by drugs (NSAID's), alcohol, H. pylori infection, etc.

  • Gastric ulcer

    • An erosion or break in the continuity of gastric mucosa (inner lining) characterised by pain, especially after meals and bleeding sometimes. 

    • Gastric ulcers can be benign (peptic ulcer) or malignant

  • Stomach or gastric cancer

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Common Investigations for gastric disorders

  • Upper GI Endoscopy (UGIE) 

    • A flexible fibre optic tube with a camera on its end (endoscope) is inserted through the mouth. The endoscope allows examination of the esophagus, stomach, and duodenum 

    • Biopsy if necessary can be taken

    • Endoscopy can be both diagnostic & therapeutic 

  • Computed tomography (CT scan)

    • Mainly to evaluate gastric tumors 

  • Magnetic resonance imaging (MRI)

  • Barium meal

    • It is the x ray taken after swallowing radio opaque material such as barium sulfate

    • It delineates contour of the stomach

Treatment of stomach disorders

  • Dyspepsia, GERD, Gastritis and Gastric ulcers

    • Acid suppressing drugs such as PPI (Proton Pump Inhibitors), H2 blockers, antacids and motility agents

  • Therapeutic Endoscopy

    • For eg- variceal banding for bleeding, stricture dilatation & stenting etc.

  • Anti H.Pylori drugs for H.Pylori infection

  • Gastric  surgeries

    • D2 Gastrectomy ( Partial or Total) for Gastric cancers

    • Vagotomy for ulcers

    • Gastro-jejunsotomy for obstruction

    • Bariatric Surgeries for obesity ( Laparoscopic sleeve gastrectomy, Laparoscopic RYGJ, Laparoscopic MGB (Mini Gastric Bypass) etc.

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Discussion 

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Clinic Address: Mysore

Impulse Medical Center, Near Vidyashrama College, Temple Road, Mysore-570012 

Clinic Address: Mandya

Sattva Health Care, Behind TVS show room, 100 feet Raod, Mandya -571401 

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