The liver is a solid gastrointestinal organ weighing around 1.5 kgs, situated in the right upper quadrant of the abdomen largely under the rib cage. So,  normal liver is not palpable. It is reddish-brown in colour and feels rubbery to touch

• The liver has right and left lobes. Gallbladder is situated under the liver

• Unlike other organs, liver has dual blood supply (Portal vein & Hepatic artery)

• Liver blood flow represents about 25% of the cardiac output 

• Liver blood flow is decreased during exercise and increased after ingestion of food

• Liver filters the portal blood coming from the digestive tract before reaching the heart and rest of the body

• The liver is the only visceral organ that can regenerate

Major functions of the liver 

• Bile production and excretion - helps in digestion and absorption of fats & fat soluble vitamins (A,D,E & K)

• Excretion of bilirubin, cholesterol, hormones, and drugs

• Metabolism of fats, proteins, and carbohydrates

• Storage of glycogen, vitamins (A,D,E,K & B12), and minerals (iron,copper)

• Synthesis of plasma proteins, such as albumin, and clotting factors (2,7,9 &10)

• Blood detoxification and purification